Tom Wei-Wu Chen , MD, PhD

Dr. Tom W. Chen’s Story

Dr. Tom W. Chen is an attending physician at the Department of Oncology, National Taiwan University Hospital (NTUH) in Taipei, Taiwan. Dr. Chen received internal medicine training followed by a fellowship course as a medical oncologist in NTUH. Afterwards, he joined Drug Development Program (DDP) in Princess Margaret Cancer Centre in Toronto, Canada as a clinical fellow to study early phase clinical trials with Dr. Lillian Siu and Dr. Phil Bedard. After returning to NTUH, he facilitated the establishment of sarcoma multi-disciplinary team. He is actively involved in many global sarcoma clinical trials as well as investigator-initiated clinical trials in soft tissue sarcoma. He is the PI of the LEADER study, which tests the combination of lenvatinib and eribulin in leiomyosarcoma and liposarcoma and the abstract was selected for oral presentation in the ASCO 2020 Virtual Meeting. He also collaborated with the Dr. Wolf Fridman and Catherine Sautes-Fridman of the Cordelier Research Center in Paris to investigate the immune microenvironment of soft tissue sarcoma. The collaborative research demonstrated the importance of B cells and tertiary lymphoid structure in soft tissue sarcoma was published in Nature. He also actively participated in many international sarcoma groups including Asia Sarcoma Consortium and World Sarcoma Network. He was appointed the Sarcoma Scientific Chair of ESMO Asia 2019 and more recently Sarcoma Scientific Chair of ESMO 2022.

Research Interest

Clinical trial methodology, research for cancer patients

Department

Oncology

Professional Experience

ESMO Congress 2019,2022 Scientific Committee Track Chair

Editorial Board of the international journal Therapeutic Advances

Taiwan oncology society Deputy secretary General

Taiwan society of cancer palliative medicine certificate

Attending physician at the Department of Oncology, National Taiwan University Hospital (NTUH) in Taipei, Taiwan.

Specialized field

Sarcoma, Breast

Qualifications, certified physicians, medical specialists

Attending physician

研究実績

Soft tissue sarcoma incidences and clinical characteristics are significantly different in France and Taiwan

Tom Wei-Wu Chen, Ruru Chun-Ju Chiang, Alex Le Cesne, Yu-Chun Hsieh, Antoine Italiano, Ya-Wen Yang, Nicolas Penel, Wen-Chung Lee, Emmanuelle Bompas, Thibaud Valentin, Philippe Anract, Nelly Firmin, Florence Duffaud, Ann-Lii Cheng, Francoise Ducimetiere, K Arnold Chan, Jean-Yves Blay

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Spectrum of cancer patients receiving renal biopsy

Fan-Chi Chang, Tom Wei-Wu Chen, Thomas Tao-Min Huang, Wei-Chou Lin, Jia-Sin Liu, Wen-Chih Chiang, Yung-Ming Chen, Chiun Hsu, Kun-Huei Yeh, Tzong-Shinn Chu

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The treatment landscape of advanced angiosarcoma in Asia-A multi-national collaboration from the Asian Sarcoma Consortium

Tom Wei-Wu Chen, Angela Pang, Mark E Puhaindran, Myo Myint Maw, Herbert H Loong, Virote Sriuranpong, Chih-Chi Chang, Siyamol Mingmalairak, Takeshi Hirose, Makoto Endo, Akira Kawai, Mohamad Farid, Sze Huey Tan, Wei Lin Goh, Richard Quek, Jeffrey C H Chan, Alex K C Leung, Roger K C Ngan

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Tazemetostat in advanced epithelioid sarcoma with loss of INI1/SMARCB1: an international, open-label, phase 2 basket study

Mrinal Gounder, Patrick Schöffski, Robin L Jones, Mark Agulnik, Gregory M Cote, Victor M Villalobos, Steven Attia, Rashmi Chugh, Tom Wei-Wu Chen, Thierry Jahan, Elizabeth T Loggers, Abha GuptaAntoine Italiano, George D Demetri, Ravin Ratan, Lara E Davis, Olivier Mir, Palma Dileo, Brian A Van Tine, Shefali Agarwal, Silvia Stacchiotti , et al.

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Systemic treatment of breast cancer with leptomeningeal metastases using bevacizumab, etoposide and cisplatin (BEEP regimen) significantly improves overall survival

Tom Wei-Wu Chen, I-Shiow Jan, Dwang-Ying Chang, Ching-Hung Lin, I-Chun Chen, Ho-Min Chen, Ann-Lii Cheng, Yen-Shen Lu

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A phase I study of pexidartinib, a colony-stimulating factor 1 receptor inhibitor, in Asian patients with advanced solid tumors

Jih-Hsiang Lee, Tom Wei-Wu Chen, Chih-Hung Hsu, Yu-Hsin Yen, James Chih-Hsin Yang, Ann-Lii Cheng, Shun-Ichi Sasaki, LiYin Lillian Chiu, Masahiro Sugihara, Tomoko Ishizuka, Toshihiro Oguma, Naoyuki Tajima, Chia-Chi Lin

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B cells are associated with survival and immunotherapy response in sarcoma

Florent Petitprez, Aurélien de Reyniès, Emily Z Keung, Tom Wei-Wu Chen, Cheng-Ming Sun, Julien Calderaro, Yung-Ming Jeng, Li-Ping Hsiao, Laetitia Lacroix, Antoine Bougoüin, Marco Moreira, Guillaume Lacroix, Ivo Natario, Julien Adam, Carlo Lucchesi, Yec Han Laizet, Maud Toulmonde, Melissa A Burgess, Vanessa Bolejack, Catherine Sautès-Fridman , et al.

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Primary cardiac sarcomas: A multi-national retrospective review

Tom Wei-Wu Chen, Herbert H Loong, Amirrtha Srikanthan, Alona Zer, Reeta Barua, Jagdish Butany, Robert J Cusimano, Yun-Chieh Liang, Chin-Hao Chang, Zaza Iakobishvili, Albiruni R Abdul Razak, Jeremy Lewin

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A Phase I/II study of the combination of lapatinib and oral vinorelbine in HER2-positive metastatic breast cancer

Tom Wei-Wu Chen, Dah-Cherng Yeh, Tsu-Yi Chao, Ching-Hung Lin, Louis Wing-Cheong Chow, Dwan-Ying Chang, Yao-Yu Hsieh, Shu-Min Huang, Ann-Lii Cheng, Yen-Shen Lu, Taiwan Breast Cancer Consortium

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Impact of multi-gene mutational profiling on clinical trial outcomes in metastatic breast cancer

Rossanna C Pezo, Tom W Chen, Hal K Berman, Anna M Mulligan, Albiruni A Razak, Lillian L Siu, David W Cescon, Eitan Amir, Christine Elser, David G Warr, Srikala S Sridhar, Celeste Yu, Lisa Wang, Tracy L Stockley, Suzanne Kamel-Reid, Philippe L Bedard

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