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After I graduated medical school, I entered in a Ph.D. course of basic pathology lab where I researched tumorigenesis and drug resistance of glioma. Then, I spent two years at Memorial Sloan Kettering Cancer Center as a postdoc and pursuited the molecular target in sarcoma using next-genaration sequencing. I identified that a mutation in MYOD1 gene, a transcription factor regulating the muscle differentiation, is involed in tumorgenesis of sarcoma. After coming back to Japan, I joined Dr. Mano’s lab and started in a study to develop Todai OncoPanel, a cancer panel testing, and the MANO method, a high-throughput functional assay for gene variants.
I am interesed in molecular target identification to progress the new drug development. I am also keen on the construction of new assay using cutting-edge technologies. I am currently building assays for liquid biopsy.
2020-Present | Chief, Division of Cellular Signaling, National Cancer Center Research Institute. |
2017-2020 | Senior Staff Scientist, Division of Cellular Signaling, National Cancer Center Research Institute. |
2015-2017 | Assistant professor, Division of Cellular Signaling, Graduate School of Medicine, The University of Tokyo. |
2012-2014 | Fellow, Molecular Pathology & Diagnostics, Memorial Sloan-Kettering Cancer Center, NY. |
2011-2012 | Fellow, Department of Cancer Pathology, Hokkaido University Graduate School of Medicine. |