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ATLAS Asia Clinical Trials Network for Cancers Project
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  3. Shinji Kohsaka (高阪 真路)

Shinji Kohsaka (高阪 真路) , MD, PhD

Title (Affiliation)
Group for Cancer Development and Progression, Division of Cellular Signaling
Facility Name

National Cancer Center Hospital, Japan

高阪 真路の写真

Dr. KOHSAKA’s Story

After I graduated medical school, I entered in a Ph.D. course of basic pathology lab where I researched tumorigenesis and drug resistance of glioma. Then, I spent two years at Memorial Sloan Kettering Cancer Center as a postdoc and pursuited the molecular target in sarcoma using next-genaration sequencing. I identified that a mutation in MYOD1 gene, a transcription factor regulating the muscle differentiation, is involed in tumorgenesis of sarcoma. After coming back to Japan, I joined Dr. Mano’s lab and started in a study to develop Todai OncoPanel, a cancer panel testing, and the MANO method, a high-throughput functional assay for gene variants.

Research Interest

I am interesed in molecular target identification to progress the new drug development. I am also keen on the construction of new assay using cutting-edge technologies. I am currently building assays for liquid biopsy.

Professional Experience

2020-Present Chief, Division of Cellular Signaling, National Cancer Center Research Institute.
2017-2020 Senior Staff Scientist, Division of Cellular Signaling, National Cancer Center Research Institute.
2015-2017 Assistant professor, Division of Cellular Signaling, Graduate School of Medicine, The University of Tokyo.
2012-2014 Fellow, Molecular Pathology & Diagnostics, Memorial Sloan-Kettering Cancer Center, NY.
2011-2012 Fellow, Department of Cancer Pathology, Hokkaido University Graduate School of Medicine.

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