{"id":3528,"date":"2025-09-05T16:36:08","date_gmt":"2025-09-05T07:36:08","guid":{"rendered":"https:\/\/atlas.ncc.go.jp\/member_search\/3528"},"modified":"2025-09-05T16:36:08","modified_gmt":"2025-09-05T07:36:08","slug":"%e9%ab%98%e9%98%aa%e3%80%80%e7%9c%9f%e8%b7%af","status":"publish","type":"researcher","link":"https:\/\/atlas.ncc.go.jp\/en\/member_search\/3528","title":{"rendered":"Shinji Kohsaka EN"},"template":"","class_list":["post-3528","researcher","type-researcher","status-publish","hentry","en-US"],"acf":{"name_eg":"Shinji Kohsaka ","familyName_eg":"Kohsaka","has_jp_name":true,"name_jp":"\u9ad8\u962a\u3000\u771f\u8def","researcher_photo":921,"participated_in":["1","2"],"degree":"MD, PhD","position":"Group for Cancer Development and Progression, Division of Cellular Signaling","eg_position":"Group for Cancer Development and Progression, Division of Cellular Signaling","facilities":3399,"department":[],"speciality":"","eg_speciality":"","background":"

Dr. KOHSAKA's Story<\/h2>\r\n

After I graduated medical school, I entered in a Ph.D. course of basic pathology lab where I researched tumorigenesis and drug resistance of glioma. Then, I spent two years at Memorial Sloan Kettering Cancer Center as a postdoc and pursuited the molecular target in sarcoma using next-genaration sequencing. I identified that a mutation in MYOD1 gene, a transcription factor regulating the muscle differentiation, is involed in tumorgenesis of sarcoma. After coming back to Japan, I joined Dr. Mano's lab and started in a study to develop Todai OncoPanel, a cancer panel testing, and the MANO method, a high-throughput functional assay for gene variants.<\/p>\r\n

Research Interest<\/h2>\r\n

I am interesed in molecular target identification to progress the new drug development. I am also keen on the construction of new assay using cutting-edge technologies. I am currently building assays for liquid biopsy.<\/p>\r\n

Professional Experience<\/h2>\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n
2020-Present<\/td>\r\nChief, Division of Cellular Signaling, National Cancer Center Research Institute.<\/td>\r\n<\/tr>\r\n
2017-2020<\/td>\r\nSenior Staff Scientist, Division of Cellular Signaling, National Cancer Center Research Institute.<\/td>\r\n<\/tr>\r\n
2015-2017<\/td>\r\nAssistant professor, Division of Cellular Signaling, Graduate School of Medicine, The University of Tokyo.<\/td>\r\n<\/tr>\r\n
2012-2014<\/td>\r\nFellow, Molecular Pathology & Diagnostics, Memorial Sloan-Kettering Cancer Center, NY.<\/td>\r\n<\/tr>\r\n
2011-2012<\/td>\r\nFellow, Department of Cancer Pathology, Hokkaido University Graduate School of Medicine.<\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\n


\r\n
\r\n<\/h2>","eg_background":"

Dr. KOHSAKA's Story<\/h2>\r\n

After I graduated medical school, I entered in a Ph.D. course of basic pathology lab where I researched tumorigenesis and drug resistance of glioma. Then, I spent two years at Memorial Sloan Kettering Cancer Center as a postdoc and pursuited the molecular target in sarcoma using next-genaration sequencing. I identified that a mutation in MYOD1 gene, a transcription factor regulating the muscle differentiation, is involed in tumorgenesis of sarcoma. After coming back to Japan, I joined Dr. Mano's lab and started in a study to develop Todai OncoPanel, a cancer panel testing, and the MANO method, a high-throughput functional assay for gene variants.<\/p>\r\n

Research Interest<\/h2>\r\n

I am interesed in molecular target identification to progress the new drug development. I am also keen on the construction of new assay using cutting-edge technologies. I am currently building assays for liquid biopsy.<\/p>\r\n

Professional Experience<\/h2>\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n
2020-Present<\/td>\r\nChief, Division of Cellular Signaling, National Cancer Center Research Institute.<\/td>\r\n<\/tr>\r\n
2017-2020<\/td>\r\nSenior Staff Scientist, Division of Cellular Signaling, National Cancer Center Research Institute.<\/td>\r\n<\/tr>\r\n
2015-2017<\/td>\r\nAssistant professor, Division of Cellular Signaling, Graduate School of Medicine, The University of Tokyo.<\/td>\r\n<\/tr>\r\n
2012-2014<\/td>\r\nFellow, Molecular Pathology & Diagnostics, Memorial Sloan-Kettering Cancer Center, NY.<\/td>\r\n<\/tr>\r\n
2011-2012<\/td>\r\nFellow, Department of Cancer Pathology, Hokkaido University Graduate School of Medicine.<\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>","researcher_outerlink1":"","researcher_outerlink2":"","researcher_outerlink3":"","researcher_outerlink4":"","researcher_outerlink5":"","is_retired":false},"_links":{"self":[{"href":"https:\/\/atlas.ncc.go.jp\/wp-json\/wp\/v2\/researcher\/3528","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/atlas.ncc.go.jp\/wp-json\/wp\/v2\/researcher"}],"about":[{"href":"https:\/\/atlas.ncc.go.jp\/wp-json\/wp\/v2\/types\/researcher"}],"acf:post":[{"embeddable":true,"href":"https:\/\/atlas.ncc.go.jp\/wp-json\/wp\/v2\/facility\/3399"}],"wp:attachment":[{"href":"https:\/\/atlas.ncc.go.jp\/wp-json\/wp\/v2\/media?parent=3528"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}