{"id":3525,"date":"2025-09-05T16:38:18","date_gmt":"2025-09-05T07:38:18","guid":{"rendered":"https:\/\/atlas.ncc.go.jp\/member_search\/3525"},"modified":"2025-09-05T16:38:21","modified_gmt":"2025-09-05T07:38:21","slug":"%e9%96%93%e9%87%8e%e3%80%80%e5%8d%9a%e8%a1%8c","status":"publish","type":"researcher","link":"https:\/\/atlas.ncc.go.jp\/en\/member_search\/3525","title":{"rendered":"Hiroyuki Mano EN"},"template":"","class_list":["post-3525","researcher","type-researcher","status-publish","hentry","en-US"],"acf":{"name_eg":"Hiroyuki Mano","familyName_eg":"Mano","has_jp_name":true,"name_jp":"\u9593\u91ce\u3000\u535a\u884c","researcher_photo":984,"participated_in":["-1"],"degree":"MD, PhD","position":"Director","eg_position":"Director","facilities":3399,"department":[],"speciality":"","eg_speciality":"","background":"<h2><strong>Dr. Mano's Story<\/strong><\/h2>\r\n<p>I graduated from School of Medicine, The University of Tokyo in 1984, and became a clinical hematologist. Knowing few effective treatments against human cancer, I was deeply engaged in the research for the identification of essential growth-drivers in cancer. I could indeed discover EML4-ALK oncogene when I was a professor at Jichi Medical University, and also find crizotinib-resistant mutations within EML4-ALK and DUX4-IGH oncogene when I was a professor at The University of Tokyo. With these achievements, I was awarded The Medal of Honor with Purple Ribbon from The Japanese Emperor, The Keio Medical Science Prize, The Japan Academy Prize, and The L\u00e9pold Griffuel Award (from France). I am also a member of The Japan Academy. In the ATLAS project, I am wishing to support the genomic medicine part.<\/p>\r\n<h2><strong>Research Interest<\/strong><\/h2>\r\n<p>My expertise is medical genomics and molecular oncology, but my personal goal is to, with the power of science, save the life of as many cancer patients as possible.<\/p>\r\n<h2><strong>Professional Experience<\/strong><\/h2>\r\n<table class=\"table1\" style=\"border-collapse: collapse; width: 100%;\">\r\n<tbody>\r\n<tr>\r\n<td style=\"width: 49.8864%;\">2021-present<\/td>\r\n<td style=\"width: 50%;\">Member of The Japan Academy<\/td>\r\n<\/tr>\r\n<tr>\r\n<td style=\"width: 49.8864%;\">2018-present<\/td>\r\n<td style=\"width: 50%;\">Director, Center for Cancer Genomics and Advanced Therapeutics (C-CAT), National Cancer Center<\/td>\r\n<\/tr>\r\n<tr>\r\n<td style=\"width: 49.8864%;\">2016-present<\/td>\r\n<td style=\"width: 50%;\">Director, Research Institute, National Cancer Center<\/td>\r\n<\/tr>\r\n<tr>\r\n<td style=\"width: 49.8864%;\">2013-2018<\/td>\r\n<td style=\"width: 50%;\">Professor, Department of Cellular Signaling, Graudate School of Medicine, The University of Tokyo<\/td>\r\n<\/tr>\r\n<tr>\r\n<td style=\"width: 49.8864%;\">2001-2013<\/td>\r\n<td style=\"width: 50%;\">Professor, Division of Funtional Genomics, Jichi Medical University<\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>","eg_background":"<h2><strong>Dr. Mano's Story<\/strong><\/h2>\r\n<p>I graduated from School of Medicine, The University of Tokyo in 1984, and became a clinical hematologist. Knowing few effective treatments against human cancer, I was deeply engaged in the research for the identification of essential growth-drivers in cancer. I could indeed discover EML4-ALK oncogene when I was a professor at Jichi Medical University, and also find crizotinib-resistant mutations within EML4-ALK and DUX4-IGH oncogene when I was a professor at The University of Tokyo. With these achievements, I was awarded The Medal of Honor with Purple Ribbon from The Japanese Emperor, The Keio Medical Science Prize, The Japan Academy Prize, and The L\u00e9pold Griffuel Award (from France). I am also a member of The Japan Academy. In the ATLAS project, I am wishing to support the genomic medicine part.<\/p>\r\n<h2><strong>Research Interest<\/strong><\/h2>\r\n<p>My expertise is medical genomics and molecular oncology, but my personal goal is to, with the power of science, save the life of as many cancer patients as possible.<\/p>\r\n<h2><strong>Professional Experience<\/strong><\/h2>\r\n<table style=\"border-collapse: collapse; width: 100%;\">\r\n<tbody>\r\n<tr>\r\n<td style=\"width: 49.8864%;\">2021-present<\/td>\r\n<td style=\"width: 50%;\">Member of The Japan Academy<\/td>\r\n<\/tr>\r\n<tr>\r\n<td style=\"width: 49.8864%;\">2018-present<\/td>\r\n<td style=\"width: 50%;\">Director, Center for Cancer Genomics and Advanced Therapeutics (C-CAT), National Cancer Center<\/td>\r\n<\/tr>\r\n<tr>\r\n<td style=\"width: 49.8864%;\">2016-present<\/td>\r\n<td style=\"width: 50%;\">Director, Research Institute, National Cancer Center<\/td>\r\n<\/tr>\r\n<tr>\r\n<td style=\"width: 49.8864%;\">2013-2018<\/td>\r\n<td style=\"width: 50%;\">Professor, Department of Cellular Signaling, Graudate School of Medicine, The University of Tokyo<\/td>\r\n<\/tr>\r\n<tr>\r\n<td style=\"width: 49.8864%;\">2001-2013<\/td>\r\n<td style=\"width: 50%;\">Professor, Division of Funtional Genomics, Jichi Medical University<\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>","researcher_outerlink1":"","researcher_outerlink2":"","researcher_outerlink3":"","researcher_outerlink4":"","researcher_outerlink5":"","is_retired":false},"_links":{"self":[{"href":"https:\/\/atlas.ncc.go.jp\/wp-json\/wp\/v2\/researcher\/3525","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/atlas.ncc.go.jp\/wp-json\/wp\/v2\/researcher"}],"about":[{"href":"https:\/\/atlas.ncc.go.jp\/wp-json\/wp\/v2\/types\/researcher"}],"acf:post":[{"embeddable":true,"href":"https:\/\/atlas.ncc.go.jp\/wp-json\/wp\/v2\/facility\/3399"}],"wp:attachment":[{"href":"https:\/\/atlas.ncc.go.jp\/wp-json\/wp\/v2\/media?parent=3525"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}