{"id":3570,"date":"2024-01-22T13:43:56","date_gmt":"2024-01-22T04:43:56","guid":{"rendered":"https:\/\/atlas.ncc.go.jp\/international_care\/ncc_today\/3570"},"modified":"2025-09-18T15:24:11","modified_gmt":"2025-09-18T06:24:11","slug":"%e6%97%a9%e6%9c%9f%e8%86%b5%e7%99%8c%e8%a8%ba%e6%96%ad%e3%81%b8%e3%81%ae%e6%8c%91%e6%88%a6","status":"publish","type":"imcs_blog","link":"https:\/\/atlas.ncc.go.jp\/en\/international_care\/ncc_today\/3570","title":{"rendered":"Challenges in diagnosing early-stage pancreatic cancer"},"template":"","class_list":["post-3570","imcs_blog","type-imcs_blog","status-publish","hentry","en-US"],"acf":{"title_en":"Challenges in diagnosing early-stage pancreatic cancer","from":{"jp":"Yoshikuni Nagashio","en":"Yoshikuni Nagashio"},"content":{"jp":"<p style=\"text-align: right;\">2024\/1\/22<\/p>\r\n<p>In order to improve the outcome of pancreatic cancer treatment, it is important to accurately diagnose pancreatic tumors at a smaller level in addition to developing new drugs and other treatments. Early-stage pancreatic cancer with a promising long-term prognosis by surgical resection is said to be a tumor less than 1 cm in diameter. However, most pancreatic tumors smaller than 1 cm in diameter cannot be detected by CT or MRI. To diagnose early-stage pancreatic cancer in which the tumor itself cannot be detected by CT or MRI, we focus on the indirect findings of pancreatic cancer such as stenosis\/dilation of the main pancreatic duct and atrophy of the pancreatic parenchyma. Using endoscopic ultrasonography (EUS), we examine the pancreas for early-stage pancreatic cancer, including areas where these findings are present.<\/p>\r\n<p>EUS is an endoscope with a high-resolution ultrasound tip. If a tumor can be visualized by EUS, EUS- guided tissue acquisition (EUS-TA) is performed to confirm the diagnosis. In cases of suspected early-stage pancreatic cancer in which the tumor cannot be visualized by EUS, endoscopic retrograde cholangiopancreatography (ERCP) is used to diagnose early-stage pancreatic cancer.<\/p>\r\n<p><img src=\"https:\/\/atlas.ncc.go.jp\/atlasprj_cms\/wp-content\/uploads\/\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2024-01-22-113333.png\" alt=\"\" width=\"1459\" height=\"565\" class=\"alignnone size-full wp-image-2310\" \/><\/p>\r\n<p><img src=\"https:\/\/atlas.ncc.go.jp\/atlasprj_cms\/wp-content\/uploads\/\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2024-01-22-113452.png\" alt=\"\" width=\"1366\" height=\"634\" class=\"alignnone size-full wp-image-2311\" \/><\/p>\r\n<p><img src=\"https:\/\/atlas.ncc.go.jp\/atlasprj_cms\/wp-content\/uploads\/\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2024-01-22-113703.png\" alt=\"\" width=\"1510\" height=\"673\" class=\"alignnone size-full wp-image-2312\" \/><\/p>\r\n<p><img src=\"https:\/\/atlas.ncc.go.jp\/atlasprj_cms\/wp-content\/uploads\/\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2024-01-22-113755.png\" alt=\"\" width=\"1453\" height=\"834\" class=\"alignnone size-full wp-image-2313\" \/><\/p>","en":"<p style=\"text-align: right;\">2024\/1\/22<\/p>\r\n<p>In order to improve the outcome of pancreatic cancer treatment, it is important to accurately diagnose pancreatic tumors at a smaller level in addition to developing new drugs and other treatments. Early-stage pancreatic cancer with a promising long-term prognosis by surgical resection is said to be a tumor less than 1 cm in diameter. However, most pancreatic tumors smaller than 1 cm in diameter cannot be detected by CT or MRI. To diagnose early-stage pancreatic cancer in which the tumor itself cannot be detected by CT or MRI, we focus on the indirect findings of pancreatic cancer such as stenosis\/dilation of the main pancreatic duct and atrophy of the pancreatic parenchyma. Using endoscopic ultrasonography (EUS), we examine the pancreas for early-stage pancreatic cancer, including areas where these findings are present.<\/p>\r\n<p>EUS is an endoscope with a high-resolution ultrasound tip. If a tumor can be visualized by EUS, EUS- guided tissue acquisition (EUS-TA) is performed to confirm the diagnosis. In cases of suspected early-stage pancreatic cancer in which the tumor cannot be visualized by EUS, endoscopic retrograde cholangiopancreatography (ERCP) is used to diagnose early-stage pancreatic cancer.<\/p>\r\n<p><img src=\"https:\/\/atlas.ncc.go.jp\/atlasprj_cms\/wp-content\/uploads\/\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2024-01-22-113333.png\" alt=\"\" width=\"1459\" height=\"565\" class=\"alignnone size-full wp-image-2310\" \/><\/p>\r\n<p><img src=\"https:\/\/atlas.ncc.go.jp\/atlasprj_cms\/wp-content\/uploads\/\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2024-01-22-113452.png\" alt=\"\" width=\"1366\" height=\"634\" class=\"alignnone size-full wp-image-2311\" \/><\/p>\r\n<p><img src=\"https:\/\/atlas.ncc.go.jp\/atlasprj_cms\/wp-content\/uploads\/\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2024-01-22-113703.png\" alt=\"\" width=\"1510\" height=\"673\" class=\"alignnone size-full wp-image-2312\" \/><\/p>\r\n<p><img src=\"https:\/\/atlas.ncc.go.jp\/atlasprj_cms\/wp-content\/uploads\/\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2024-01-22-113755.png\" alt=\"\" width=\"1453\" height=\"834\" class=\"alignnone size-full wp-image-2313\" \/><\/p>"},"thumbnail":2314,"show_in_detail":true,"show_in_topics":["0","4"],"show_in_imcs_dept":["17"]},"_links":{"self":[{"href":"https:\/\/atlas.ncc.go.jp\/wp-json\/wp\/v2\/imcs_blog\/3570","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/atlas.ncc.go.jp\/wp-json\/wp\/v2\/imcs_blog"}],"about":[{"href":"https:\/\/atlas.ncc.go.jp\/wp-json\/wp\/v2\/types\/imcs_blog"}],"wp:attachment":[{"href":"https:\/\/atlas.ncc.go.jp\/wp-json\/wp\/v2\/media?parent=3570"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}